# The Lab Guy

> Pablo J. Lebed is an Analytical Chemist specializing in ICP-MS, ICP-OES, method validation, uncertainty budgets, and laboratory data analysis. This site hosts interactive chemistry tools, simulations, and technical notes for the analytical chemistry community.

The Lab Guy (thelabguy.org) is a personal portfolio and technical knowledge-base. It is a free, publicly accessible resource with no login required. All tools run entirely in the browser with no data sent to any server.

## Technical Notes

- [Running a Clean ICP-MS Batch](https://thelabguy.org/note/icpms-quality-gates): A practical 5-gate quality checklist for validating ICP-MS data before it leaves the lab. Covers kinetic/thermal optimization, back-pressure, mass calibration, internal standards, and blank correction.
- [SPC & Uncertainty Calculation](https://thelabguy.org/note/spc-uncertainty-calculation): Statistical Process Control charting and measurement uncertainty budget construction using Root Sum of Squares (RSS) methodology.
- [Battery Method Validation](https://thelabguy.org/note/battery-method-validation): Full method validation walkthrough for elemental analysis in battery materials, including specificity, linearity, accuracy, precision, LOD/LOQ, range, robustness, and uncertainty.

## Interactive Tools

- [Calibration Engine](https://thelabguy.org/tools/calibration-engine): Build analytical calibration curves with weighted regression, visualise residuals, and evaluate fit quality for ICP-MS/ICP-OES methods.
- [ICP Torch Simulation](https://thelabguy.org/simulation/icp-torch): Interactive 3D simulation of an Inductively Coupled Plasma torch — explore plasma zones, temperature gradients, and sample introduction.
- [LOD/LOQ Calculator](https://thelabguy.org/tools/lod-loq-calculator): Estimate Limit of Detection and Limit of Quantification using Signal-to-Noise and Calibration Residual methods.
- [Uncertainty Budget Calculator](https://thelabguy.org/tools/uncertainty-budget): Build a GUM-compliant measurement uncertainty budget combining calibration, precision, bias, and volume contributions.
- [Precision Calculator](https://thelabguy.org/tools/precision-calculator): Compute repeatability and intermediate precision using pooled-variance decomposition per ICH Q2(R2) / ISO 5725.
- [Accuracy Calculator](https://thelabguy.org/tools/accuracy-calculator): Calculate spike recovery, standard deviation, and RSD for method accuracy validation across multiple concentration levels.
- [Linearity Calculator](https://thelabguy.org/tools/linearity-calculator): Assess calibration linearity with regression analysis, Pearson r, residual plots, and intercept significance testing.
- [Specificity Calculator](https://thelabguy.org/tools/specificity-calculator): Evaluate method specificity by comparing blank, sample, and spiked responses to assess interference and selectivity.
- [Range Calculator](https://thelabguy.org/tools/range-calculator): Determine the validated working range of an analytical method by evaluating recovery and precision at boundary concentrations.
- [Robustness Calculator](https://thelabguy.org/tools/robustness-calculator): Evaluate method robustness using Youden-style factorial experiments to identify critical factors.
- [Validation Summary Dashboard](https://thelabguy.org/tools/validation-summary): Review all eight method validation parameters in one consolidated dashboard.

## About

- [Resume — Pablo J. Lebed](https://thelabguy.org/resume): Professional CV covering ICP-MS, ICP-OES, elemental analysis, method validation, and laboratory quality systems experience.
- [The Why Corner](https://thelabguy.org/the-why-corner): Educational content exploring the science behind analytical chemistry — plasma physics, spectral analysis, and instrument design.
- [News](https://thelabguy.org/news): Latest updates, new tools, and announcements.